CRISPR Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
HTT Huntingtin protein maintains balanced energetics in mouse cardiomyocytes Nucleosides Nucleotides Nucleic Acids, 2020 Sep CRISPR KN308042
HTT ATP and spontaneous calcium oscillations control neural stem cell fate determination in Huntington\'s disease: a novel approach for cell clock research Mol. Psychiatry, 2020 Apr CRISPR KN308042
Ido1 Dual inhibition of IDO1/TDO2 enhances anti-tumor immunity in platinum-resistant non-small cell lung cancer. Cancer & metabolism, 2023 May CRISPR KN508091
IFITM1 Disrupting interferon-alpha and NF-kappaB crosstalk suppresses IFITM1 expression attenuating triple-negative breast cancer progression Cancer letters, 2021 May CRISPR KN201617
IL1 beta Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5 Int. J. Cancer, 2019 May CRISPR KN402079
IL6 Targeting Interleukin-6 (IL-6) Sensitizes Anti-PD-L1 Treatment in a Colorectal Cancer Preclinical Model Med. Sci. Monit., 2018 Aug CRISPR KN308293
IL8 Wnt/IL-1β/IL-8 autocrine circuitries control chemoresistance in mesothelioma initiating cells by inducing ABCB5 Int. J. Cancer, 2019 May CRISPR KN202075
ITIH5 Inter-α-Trypsin Inhibitor Heavy Chain 5 (ITIH5) Is a Natural Stabilizer of Hyaluronan That Modulates Biological Processes in the Skin Skin Pharmacol Physiol, 2020 Aug CRISPR KN214478
KIF26B Genome-wide association and functional analyses identify CASC20 and KIF26B as target loci in heterotopic ossification BioRxiv, 2019 Nov CRISPR KN308785
MAMDC4 The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation Cell Mol Gastroenterol Hepatol, 2018 Nov CRISPR KN216843
MEK5 The WNK1-ERK5 route plays a pathophysiological role in ovarian cancer and limits therapeutic efficacy of trametinib. Clinical and translational medicine, 2023 Apr CRISPR KN203171
MOV10 Effect of P-body component Mov10 on HCV virus production and infectivity FASEB J., 2020 Jun CRISPR KN400934
mtTFA Mitochondrial DNA Copy Number (mtDNA-CN) Can Influence Mortality and Cardiovascular Disease via Methylation of Nuclear DNA CpGs bioRxiv, 2019 Jun CRISPR KN215488
NANS Generation of an NANS homozygous knockout human induced pluripotent stem cell line by the insertion of GFP-P2A-Puro via CRISPR/Cas9 editing. Stem cell research, 2021 Jun CRISPR KN400123
NAT1 Loss of human arylamine N-acetyltransferase I regulates mitochondrial function by inhibition of the pyruvate dehydrogenase complex Int. J. Biochem. Cell Biol., 2019 Mar CRISPR KN221042
NAT1 Arylamine N-acetyltransferase 1 protects against reactive oxygen species during glucose starvation: Role in the regulation of p53 stability PLoS ONE, 2018 Mar CRISPR KN221042
Negative Control 2-Pentadecyl-2-oxazoline ameliorates memory impairment and depression-like behaviour in neuropathic mice: possible role of adrenergic alpha2- and H3 histamine autoreceptors Molecular brain, 2021 Feb CRISPR GE100003
NEO1 Netrin-1 functions as a suppressor of bone morphogenetic protein (BMP) signaling Scientific reports, 2021 Apr CRISPR KN310902RB
NTN1 Netrin-1 functions as a suppressor of bone morphogenetic protein (BMP) signaling Scientific reports, 2021 Apr CRISPR KN511288
OGT O-GlcNAc modification of Sox2 regulates self-renewal in pancreatic cancer by promoting its stability Theranostics, 2019 May CRISPR KN206822
OGT O-GlcNAc modification of oncogenic transcription factor Sox2 promotes protein stability and regulates self-renewal in pancreatic cancer bioRxiv, 2018 Jun CRISPR KN206822
ORAI1 Genetic Manipulation of Calcium Release-Activated Calcium Channel 1 Modulates the Multipotency of Human Cartilage-Derived Mesenchymal Stem Cells Journal of Immunology Research, 2019 Feb CRISPR KN210034
OVCA1 Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing Sci Rep, 2017 Nov CRISPR KN221955
P Glycoprotein Carbonic anhydrase XII inhibitors overcome P-glycoprotein-mediated resistance to temozolomide in glioblastoma Mol. Cancer Ther., 2018 Sep CRISPR KN216080
p53 Histone deacetylase inhibitor quisinostat activates caspase signaling and upregulates p53 acetylation to inhibit the proliferation of HepG2 cells. Molecular medicine reports, 2018 Jun CRISPR KN200003
p53 mir-660-p53-mir-486 Network: A New Key Regulatory Pathway in Lung Tumorigenesis Int J Mol Sci, 2017 Jan CRISPR KN200003
pAAVS1-Puro-DNR Repurposing of KLF5 activates a cell cycle signature during the progression from a precursor state to Oesophageal Adenocarcinoma bioRxiv, 2020 Feb CRISPR GE100024
Parathyroid Hormone Receptor 1 Novel bone-targeted parathyroid hormone-related peptide antagonists inhibit breast cancer bone metastases Anti-cancer drugs, 2021 Apr CRISPR KN412841
Parkin The ubiquitin E3 ligase Parkin regulates neuronal Ca V 1.3 channel functional expression. Journal of neurophysiology, 2022 Dec CRISPR KN216186
pCas-Guide Proteomic Analysis of eIF5B Silencing-Modulated Proteostasis PLoS ONE, 2016 Dec CRISPR GE100002
pCas-Guide Cloning Mesenchymal Stem Cell Engineering Methods Mol. Biol., 2018 Sep CRISPR GE100001
pCas-Guide Cloning Kit L1 retrotransposon antisense RNA within ASAR lncRNAs controls chromosome-wide replication timing J. Cell Biol., 2017 Dec CRISPR GE100001
pCas-Guide-EF1a-GFP CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair Sci Adv, 2017 May CRISPR GE100018
pCas-Guide-GFP Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature Cancer Cell, 2017 Apr CRISPR GE100018
pCAS-Scramble Loss of USF2 promotes proliferation, migration and mitophagy in a redox-dependent manner Redox Biol, 2020 Oct CRISPR GE100003
pCas-Scramble TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation Nat Commun, 2020 Aug CRISPR GE100003
pCAS-Scramble A Safe Harbor-Targeted CRISPR/Cas9 Homology Independent Targeted Integration (HITI) System for Multi-Modality Reporter Gene-Based Cell Tracking bioRxiv, 2020 Feb CRISPR GE100003
pCAS-Scramble MAFG-driven astrocytes promote CNS inflammation Nature, 2020 Feb CRISPR GE100003
pCas-Scramble Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection Nat Commun, 2020 Feb CRISPR GE100003
pCAS-Scramble Collagen IV (COL4A1, COL4A2), a Component of the Viral Biofilm, Is Induced by the HTLV-1 Oncoprotein Tax and Impacts Virus Transmission Front Microbiol, 2019 Oct CRISPR GE100003
PGP Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death Cells, 2020 Apr CRISPR KN414470
PLAUR The Urokinase Receptor Induces a Mesenchymal Gene Expression Signature in Glioblastoma Cells and Promotes Tumor Cell Survival in Neurospheres Sci Rep, 2018 Feb CRISPR KN201222
pLenti-Cas-Guide Impact of fatty acid binding protein 5-deficiency on COPD exacerbations and cigarette smoke-induced inflammatory response to bacterial infection Clin Transl Med, 2019 Mar CRISPR GE100010
PML Protein PML plays both inimical and beneficial roles in HSV-1 replication Proc. Natl. Acad. Sci. U.S.A., 2016 May CRISPR KN200700
PPAR gamma Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L. Nature communications, 2023 Apr CRISPR KN401538
PRNP Changes in cellular prion protein expression, Processing and localization during differentiation of the neuronal cell line CAD 5 Biol. Cell, 2019 Nov CRISPR KN313942
PTEN BRCA1-Associated Protein-1 Suppresses Osteosarcoma Cell Proliferation and Migration Through Regulation PI3K/Akt Pathway DNA Cell Biol, 2017 Mar CRISPR KN202627
PTGES The COX2 effector microsomal PGE2 synthase-1 is a regulator of immunosuppression in cutaneous melanoma Clin. Cancer Res., 2018 Dec CRISPR KN314172
PTGS2 Knockdown of PTGS2 by CRISPR/CAS9 System Designates a New Potential Gene Target for Melanoma Treatment Front Pharmacol, 2019 Dec CRISPR KN314183
RECQL5 RECQL5 KIX domain splicing isoforms have distinct functions in transcription repression and DNA damage response DNA Repair, 2020 Nov CRISPR KN409460