Ptgs2 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN314183

Ptgs2 - mouse gene knockout kit via CRISPR, HDR mediated



HDR-mediated knockout kit validation

  See Other Versions

USD 1,290.00

2 Weeks*

Size
    • 1 kit

Product Images

Other products for "Ptgs2"

Specifications

Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Donor DNA GFP-puro
Symbol Ptgs2
Locus ID 19225
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_011198
Synonyms Cox-2; COX2; gripghs; PES-2; PGHS-2; Pghs2; PHS-2; PHS II; TIS10
Summary This gene encodes an enzyme that is a member of the prostaglandin G/H synthase family. The encoded protein converts arachidonic acid to prostaglandin endoperoxide H2 which is a key enzymatic step in prostaglandin biosynthesis. This gene is the inducible prostaglandin G/H synthase family member that is upregulated during inflammation. Aberrant regulation of this gene is associated with cancer progression in several tissues and an increased risk of cardiovascular events. This gene is the target of many non-steroidal anti-inflammatory drugs. [provided by RefSeq, Sep 2015]

Other Versions

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.