Ptgs2 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN514183
Ptgs2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Ptgs2 |
Locus ID | 19225 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_011198 |
Synonyms | Cox-2; COX2; gripghs; PES-2; PGHS-2; Pghs2; PHS-2; PHS II; TIS10 |
Summary | This gene encodes an enzyme that is a member of the prostaglandin G/H synthase family. The encoded protein converts arachidonic acid to prostaglandin endoperoxide H2 which is a key enzymatic step in prostaglandin biosynthesis. This gene is the inducible prostaglandin G/H synthase family member that is upregulated during inflammation. Aberrant regulation of this gene is associated with cancer progression in several tissues and an increased risk of cardiovascular events. This gene is the target of many non-steroidal anti-inflammatory drugs. [provided by RefSeq, Sep 2015] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
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KN314183 | Ptgs2 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN314183BN | Ptgs2 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN314183LP | Ptgs2 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN314183RB | Ptgs2 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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GA203460 | Ptgs2 CRISPRa kit - CRISPR gene activation of mouse prostaglandin-endoperoxide synthase 2 |
USD 1,290.00 |
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