Mouse Ptgs2 activation kit by CRISPRa

CAT#: GA203460

Ptgs2 CRISPRa kit - CRISPR gene activation of mouse prostaglandin-endoperoxide synthase 2


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Ptgs2
Locus ID 19225
Kit Components

GA203460G1, Ptgs2 gRNA vector 1 in pCas-Guide-CRISPRa

GA203460G2, Ptgs2 gRNA vector 2 in pCas-Guide-CRISPRa

GA203460G3, Ptgs2 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_011198
Synonyms Cox-2; COX2; gripghs; PES-2; PGHS-2; Pghs2; PHS-2; PHS II; TIS10
Summary This gene encodes an enzyme that is a member of the prostaglandin G/H synthase family. The encoded protein converts arachidonic acid to prostaglandin endoperoxide H2 which is a key enzymatic step in prostaglandin biosynthesis. This gene is the inducible prostaglandin G/H synthase family member that is upregulated during inflammation. Aberrant regulation of this gene is associated with cancer progression in several tissues and an increased risk of cardiovascular events. This gene is the target of many non-steroidal anti-inflammatory drugs. [provided by RefSeq, Sep 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.