shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
IFITM2 Respiratory Syncytial Virus Infection is Inhibited by Interferon-Induced Transmembrane Proteins J. Gen. Virol., 2014 Sep shRNA TG312241
IFITM3 Respiratory Syncytial Virus Infection is Inhibited by Interferon-Induced Transmembrane Proteins J. Gen. Virol., 2014 Sep shRNA TG303991
IFNAR1 Exclusive Temporal Stimulation of IL-10 Expression in LPS-Stimulated Mouse Macrophages by cAMP Inducers and Type I Interferons Front Immunol, 2019 Aug shRNA TG312233
IFNAR1 Type-1 interferons contribute to oxygen glucose deprivation induced neuro-inflammation in BE(2)M17 human neuroblastoma cells J Neuroinflammation, 2014 Mar shRNA TG312233
IFNAR1 Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease Neurobiol. Aging Dec 2013., 2013 Nov shRNA TR312233
IFNAR1 Type-1 interferon signalling mediates neuro-inflammatory events in models of Alzheimer's disease Neurobiology of Aging, 2013 Oct shRNA TG312233
IFNLR1 IL28RA inhibits human epidermal keratinocyte proliferation by inhibiting cell cycle progression. Molecular biology reports, 2019 Jul shRNA TR303938
IGF1 Acute Inflammation Induces Insulin-like Growth Factor-1 to Mediate Bcl-2 and Muc5ac Expression in Airway Epithelial Cells Am. J. Respir. Cell Mol. Biol., Dec 2012; 47: 784 - 791., 2012 Dec shRNA TG319480
IGF1 Intracellular Insulin-like Growth Factor-1 Induces Bcl-2 Expression in Airway Epithelial Cells J. Immunol., May 2012; 188: 4581 - 4589., 2012 May shRNA TR319480
IGF1R Discoidin Domain Receptor 1 functionally interacts with the IGF-I system in bladder cancer Matrix Biology Plus, 2020 Jan shRNA TG320384
IGF1R Procyanidins from Cinnamomi Cortex promote proteasome-independent degradation of nuclear Nrf2 through phosphorylation of insulin-like growth factor-1 receptor in A549 cells Arch. Biochem. Biophys., 2017 Oct shRNA TG320384
IGF1R TGFß signaling confers sorafenib resistance via induction of multiple RTKs in hepatocellular carcinoma cells Mol. Carcinog., 2016 Nov shRNA TG320384
IGF1R Regulación de la captación de glucosa en astrocitos por el eje insulina/IGF-I Thesis, 2014 Oct shRNA TG320384
IGF1R TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling Hum. Mol. Genet., Mar 2011; 10.1093/hmg/ddr076, 2011 Mar shRNA TR320384
IGF2BP3 IGF2BP3-mediated translation in cell protrusions promotes cell invasiveness and metastasis of pancreatic cancer Oncotarget, 2014 Aug shRNA TG312221
IGFBP2 Novel anti IGFBP2 single chain variable fragment inhibits glioma cell migration and invasion. Journal of neuro-oncology, 2016 Feb shRNA TR316590
IGFBP3 STAT-1 expression is regulated by IGFBP-3 in malignant glioma cells and is a strong predictor of poor survival in patients with glioblastoma J. Neurosurg., 2014 May shRNA TF312217
Igfbp4 IGFBP-4 activates the Wnt/beta-catenin signaling pathway and induces M-CAM expression in human renal cell carcinoma. International journal of cancer, 2011 Nov shRNA TL510928
IGFBP5 Genetic Screen Identifies Insulin-like Growth Factor Binding Protein 5 as a Modulator of Tamoxifen Resistance in Breast Cancer Cancer Res., Apr 2010; 70: 3013 - 3019, 2010 Apr shRNA TR316591
IGFBP7 Insulin-like growth factor-binding protein 7 alters the sensitivity to interferon-based anticancer therapy in hepatocellular carcinoma cells British Journal of Cancer (20 April 2010) doi:10.1038/sj.bjc.6605669 Full Paper, 2010 Apr shRNA TR312216
Igsf11 Promotion of differentiation in developing mouse cerebellar granule cells by a cell adhesion molecule BT-IgSF. Neuroscience letters, 2019 Mar shRNA TL506226
IHH Endogenously-produced Indian Hedgehog Regulates TGFß-driven Chondrogenesis of Human Bone Marrow Stromal/Stem Cells Stem Cells Dev., 2014 Dec shRNA TG312208
IKBKB A constitutively-active IKK-complex at the axon initial segment Brain Res., 2017 Oct shRNA TG509787
IKBKE Glucose Metabolism Reprogrammed by Overexpression of IKKe Promotes Pancreatic Tumor Growth Cancer Res, 2016 Dec shRNA TG517180
IKZF1 Regulation of Small GTPase Rab20 by Ikaros in B-Cell Acute Lymphoblastic Leukemia Int J Mol Sci, 2020 Mar shRNA TG502473
IKZF1 RAG1 high expression associated with IKZF1 dysfunction in adult B-cell acute lymphoblastic leukemia J Cancer, 2019 Jun shRNA TG502473
IKZF1 Aberrant ARID5B expression and its association with Ikaros dysfunction in acute lymphoblastic leukemia Oncogenesis, 2018 Nov shRNA TG308127
IKZF1 Ikaros regulation of the BCL6/BACH2 axis and its clinical relevance in acute lymphoblastic leukemia Oncotarget, 2017 Jan shRNA TG308127
IKZF1 Targeting High Dynamin-2 (DNM2) Expression by Restoring Ikaros Function in Acute Lymphoblastic Leukemia Sci Rep, 2016 Nov shRNA TG308127
IKZF1 Transcriptional Regulation of JARID1B/KDM5B Histone Demethylase by Ikaros, Histone Deacteylase 1 (HDAC1), and Casein Kinase 2 (CK2) in B Cell Acute Lymphoblastic Leukemia J. Biol. Chem., 2015 Dec shRNA TG308127
Il10 The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis. Journal of immunology (Baltimore, Md. : 1950), 2017 Sep shRNA TF501065
IL15RA IL15RA is required for osteoblast function and bone mineralization Bone, 2017 Oct shRNA TR501072
Il15ra Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling Oncotarget, 2017 Jan shRNA TG501072
IL18 TLR2 controls the development of hepatocellular carcinoma by reducing interleukin-18-mediated immunosuppression Cancer Res., 2015 Jan shRNA TG510212
IL1A Mitogen-Activated Protein Kinase-Dependent Interleukin-1a Intracrine Signaling Is Modulated by YopP during Yersinia enterocolitica Infection Infect. Immun., Jan 2012; 80: 289 - 297., 2012 Jan shRNA TR312183
IL1R1 Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling Oncotarget, 2017 Jan shRNA TG501076
IL22 Downregulation of miR‐26 promotes invasion and metastasis via targeting interleukin‐22 in cutaneous T‐cell lymphoma Cancer Science, 2022 Feb shRNA TL303948
IL33 Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity Stem Cell Reports, 2017 Mar shRNA MR203528
IL3RA Transcriptional regulation of SPROUTY2 by MYB influences myeloid cell proliferation and stem cell properties by enhancing responsiveness to IL-3 Leukemia, 2017 Apr shRNA TG516353
IL6 Autocrine IL-6 mediates pituitary tumor senescence Oncotarget, 2017 Jan shRNA TG709233
IL6 Harpagoside suppresses IL-6 expression in primary human osteoarthritis chondrocytes J. Orthop. Res., 2016 Apr shRNA TG312162
IL6 Metastatic Cells Can Escape the Proapoptotic Effects of TNF-a through Increased Autocrine IL-6/STAT3 Signaling Cancer Res., Feb 2012; 72: 865 - 875., 2012 Feb shRNA TR312162
IL6RA Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages Nature Immunology 12, 551-559 (24 April 2011) doi:10.1038/ni.2030 Article, 2011 Apr shRNA TR501088
IL6ST Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages Nature Immunology 12, 551-559 (24 April 2011) doi:10.1038/ni.2030 Article, 2011 Apr shRNA TR501089
ILK CCN1 induces a reversible epithelial–mesenchymal transition in gastric epithelial cells Laboratory Investigation (10 May 2010) doi:10.1038/labinvest.2010.101 Research Article, 2010 May shRNA TR712638
IMMT Mic60/mitofilin overexpression alters mitochondrial dynamics and attenuates vulnerability of dopaminergic cells to dopamine and rotenone Neurobiol. Dis., 2016 Mar shRNA TR312153
IMPDH2 IMPDH2 mediate radioresistance and chemoresistance in osteosarcoma cells Eur Rev Med Pharmacol Sci, 2014 Oct shRNA TR312150
INAVA INAVA promotes aggressiveness of papillary thyroid cancer by upregulating MMP9 expression Cell Biosci, 2018 Apr shRNA TR306059
ING1 Tumour suppressor ING1b maintains genomic stability upon replication stress Nucleic Acids Res., Jan 2011; 10.1093/nar/gkq1337, 2011 Jan shRNA TR312146
Inhba In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma Nature Communications, 2023 Jan shRNA TR516955