shRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
MDM2 Corosolic acid inhibits cancer progress through inactivating YAP in hepatocellular carcinoma Oncol. Res., 2020 Mar shRNA TG311529
MDM2 Exonuclease-1 interacts with the transcriptional co-repressor KAP1 Matters, 2016 Aug shRNA TR311529
MDM2 FATS is an E2-independent ubiquitin ligase that stabilizes p53 and promotes its activation in response to DNA damage Oncogene, 2013 Nov shRNA TG311529
MDM2 EMILIN1–a4/a9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation J. Cell Biol., Oct 2011; 195: 131 - 145., 2011 Oct shRNA TR311529
MECOM Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition Oncogene, 2016 Dec shRNA TG313148
MECOM Identifying a Potential Molecular Therapeutic Target for MLL-AF9 Leukemia Thesis, 2014 Jan shRNA TG313148
MEF2C Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths Cell Rep, 2019 Jul shRNA TF511428
Meg3 Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity Elife, 2018 Oct shRNA TG501330
MEG3 Crosstalk between Meg3 and miR-1297 regulates growth of testicular germ cell tumor through PTEN/PI3K/AKT pathway Am J Transl Res, 2016 May shRNA TG320132
MEN1 miR-29b Modulates Intestinal Epithelium Homeostasis by Repressing Menin Translation Biochem. J., 2014 Oct shRNA TG501333
MEOX1 Mesoderm/mesenchyme homeobox gene l promotes vascular smooth muscle cell phenotypic modulation and vascular remodeling Int. J. Cardiol.2017, 2017 Oct shRNA TG311507
MET FOXO1 Suppression is a Determinant of Acquired Lapatinib-Resistance in HER2-Positive Gastric Cancer Cells Through MET Upregulation Cancer Res Treat, 2017 Mar shRNA TG320418
MET Induction of tumor initiation is dependent on CD44s in c-Met(+) hepatocellular carcinoma BMC Cancer, 2015 Apr shRNA TG320418
MET Induction of tumor initiation is dependent on CD44s in c-Met+ hepatocellular carcinoma BMC Cancer, 2015 Mar shRNA TG320418
Metrnl Metrnl ameliorates diabetic cardiomyopathy via inactivation of cGAS/STING signaling dependent on LKB1/AMPK/ULK1-mediated autophagy. Journal of advanced research, 2022 Nov shRNA TL702232
MFGE8 Endometrial MFG-E8 regulates TGF-ß induced EMT promoting trophoblast invasion and implantation Reproduction, 2016 Jun shRNA TR311492
Mfn2 Mitofusin 2 Integrates Mitochondrial Network Remodelling, Mitophagy and Renewal of Respiratory Chain Proteins in Neurons after Oxygen and Glucose Deprivation. Molecular neurobiology, 2022 Sep shRNA TL712567
MGMT O(6)-Methylguanine-DNA Methyltransferase Is a Novel Negative Effector of Invasion in Glioblastoma Multiforme Mol. Cancer Ther., Nov 2012; 11: 2440 - 2450., 2012 Nov shRNA TG316615
MGP Inhibitor of DNA binding-4 promotes angiogenesis and growth of glioblastoma multiforme by elevating matrix GLA levels Oncogene (10 May 2010) doi:10.1038/onc.2010.147 Original Article, 2010 May shRNA TR311480
Mical1 Podocyte Shape Regulation by Semaphorin 3A and MICAL-1 Methods in molecular biology (Clifton, N.J.), 2018 Aug shRNA TG506165
MICAL1 Podocyte Shape Regulation by Semaphorin 3A and MICAL-1 Methods Mol. Biol., 2016 Nov shRNA TF506165
Micu2 Functional roles of MICU1 and MICU2 in mitochondrial Ca(2+) uptake. Biochimica et biophysica acta, 2016 Jul shRNA TL712808
MIF UHRF1 regulates the transcriptional repressor HBP1 through MIF in T acute lymphoblastic leukemia Oncology reports, 2021 Jul shRNA TR319111
MIF Macrophage Migration Inhibitory Factor Regulates Akt Signaling in Hypoxic Culture to Modulate Senescence of Human Mesenchymal Stem Cells Stem Cells Dev., 2013 Nov shRNA TR319111
MITF Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia J. Clin. Invest., 2019 Dec shRNA TG514672
MKRN2 Ubiquitous Expression of MAKORIN-2 in Normal and Malignant Hematopoietic Cells and Its Growth Promoting Activity PLoS ONE, 2014 Mar shRNA TG311466
MLLT11 Involvement of AF1q/MLLT11 in the progression of ovarian cancer Oncotarget, 2017 Apr shRNA TF319110
MMP1 Matrix Metalloproteinase-1 (MMP1) Upregulation through Promoter Hypomethylation Enhances Tamoxifen Resistance in Breast Cancer Cancers, 2022 Feb shRNA TL311450
MMP1 Activation of EGFR/p38/HIF-1a is pivotal for angiogenesis and tumorigenesis of malignantly transformed cells induced by hexavalent chromium J. Biol. Chem., 2016 May shRNA TG311450
MMP13 Pituitary tumor-transforming gene 1 regulates invasion of prostate cancer cells through MMP13 Tumour Biol., 2015 Jul shRNA TG311446
Mmp14 MT1-MMP silencing by an shRNA-armed glioma-targeted conditionally replicative adenovirus (CRAd) improves its anti-glioma efficacy in vitro and in vivo. Cancer letters, 2015 Oct shRNA TF510301
MMP9 MMP-9 Reinforces Radiation-Induced Delayed Invasion and Metastasis of Surviving Neuroblastoma Cells Through Second-Signaling Positive Feedback With NFkB Via Both ERK and IKK Activation Research Square, 2021 Mar shRNA TF311436
MMS19 IOP1 Protein Is an External Component of the Human Cytosolic Iron-Sulfur Cluster Assembly (CIA) Machinery and Functions in the MMS19 Protein-dependent CIA Pathway J. Biol. Chem., Jun 2013; 288: 16680 - 16689., 2013 Jun shRNA TG303224
MORC2 MORC2 regulates DNA damage response through a PARP1-dependent pathway Nucleic Acids Research, 2019 Jun shRNA TG311427
MPG Germ-line variants of human N-methylpurine DNA glycosylase show impaired DNA repair activity and facilitate 1,N6 ethenoadenine induced mutations J. Biol. Chem., 2014 Dec shRNA TR311419
MSH2 Der Einfluss des Mismatch Reparaturfaktors hMSH2 auf distinkte Reparaturwege der DNA Doppelstrangbruch Reparatur thesis, 2015 Feb shRNA TR311383
MSH3 Der Einfluss des Mismatch Reparaturfaktors hMSH2 auf distinkte Reparaturwege der DNA Doppelstrangbruch Reparatur thesis, 2015 Feb shRNA TR311382
MSH6 Der Einfluss des Mismatch Reparaturfaktors hMSH2 auf distinkte Reparaturwege der DNA Doppelstrangbruch Reparatur thesis, 2015 Feb shRNA TR311380
MSI1 Upregulation of musashi1 increases malignancy of hepatocellular carcinoma via the Wnt/β-catenin signaling pathway and predicts a poor prognosis BMC Gastroenterol, 2019 Dec shRNA TG311379
MSI1 The RNA-binding protein Musashi 1 stabilizes the onco tachykinin 1 mRNA in breast cancer cells to promote cell growth FASEB J., 2015 Sep shRNA TF311379
MSI2 Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling J. Biol. Chem., 2018 Aug shRNA TF303128
MSLN Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation Carcinogenesis, Jul 2011; 32: 1013 - 1024., 2011 Jul shRNA TR311377
msr1 Expression of scavenger receptor-AI promotes alternative activation of murine macrophages to limit hepatic inflammation and fibrosis Hepatology, 2016 Oct shRNA TR515183
MSRA Methionine sulfoxide reductase A down-regulation in human breast cancer cells results in a more aggressive phenotype PNAS, Oct 2010; 107: 18628 - 18633, 2010 Oct shRNA TR316620
MST1 MST1 Regulates Neuronal Cell Death via JNK/Casp3 Signaling Pathway in HFD Mouse Brain and HT22 Cells Int J Mol Sci, 2019 May shRNA TF514455
Mstn Myostatin induces DNA damage in skeletal muscle of streptozotocin-induced type 1 diabetic mice J. Biol. Chem., Jan 2014., 2014 Jan shRNA TG512805
MT2A Development of an Integrated Genomic Classifier for a Novel Agent in Colorectal Cancer: Approach to Individualized Therapy in Early Development Clin. Cancer Res., Jun 2010; 16: 3193 - 3204, 2010 Jun shRNA TR319082
MTA1 Mechanism of TRIM25 mediated ubiquitination of metastasis associated protein (MTA) 1 in normal liver cells Exp. Cell Res., 2018 Aug shRNA TR311372
mTOR Inactivation of the mTORC1-Eukaryotic Translation Initiation Factor 4E Pathway Alters Stress Granule Formation Mol. Cell. Biol., Jun 2013; 33: 2285 - 2301., 2013 Jun shRNA TG320364
MUC1 An intrinsic purine metabolite AICAR blocks lung tumour growth by targeting oncoprotein mucin 1 British Journal of Cancer, 2023 Feb shRNA TL316625