siRNA Citations

OriGene products have been used extensively by scientists worldwide to improve their research efficiency. For your reference, we have collected a representation of citations for selected OriGene products and posted them at this site.

Search citations by gene symbols or target names

Here are some of the recent papers making use of OriGene products by fellow researchers.

Target Research Paper Journal Product SKU
BDNF The acetylation of cyclin-dependent kinase 5 at lysine 33 regulates kinase activity and neurite length in hippocampal neurons Sci Rep, 2018 Sep siRNA SR510549
BECN1 ZBTB28 induces autophagy by regulation of FIP200 and Bcl-XL facilitating cervical cancer cell apoptosis Journal of experimental & clinical cancer research : CR, 2021 Apr siRNA SR322490
BECN1 Suppression of autophagy facilitates hydrogen gas-mediated lung cancer cell apoptosis Oncol Lett, 2020 Oct siRNA SR322490
BECN1 SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation Sci Rep, 2018 Jan siRNA SR322490
BECN1 The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux Autophagy, 2015 Jun siRNA SR305711
BECN1 GX15-070 (Obatoclax) Induces Apoptosis and Inhibits Cathepsin D- and L–Mediated Autophagosomal Lysis in Antiestrogen-Resistant Breast Cancer Cells Mol. Cancer Ther., Apr 2013; 12: 448 - 459., 2013 Apr siRNA SR305711
BHLHE40 BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver Elife, 2018 Jun siRNA SR515541
BHLHE41 Phospho-?Np63?/microRNA feedback regulation in squamous carcinoma cells upon cisplatin exposure Cell Cycle, 2013 Feb siRNA SR312407
BID BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella EMBO J. July 2014, 2014 Jul siRNA SR300435
BIN1 Podosome formation promotes plasma membrane invagination and integrin-β3 endocytosis on a viscous RGD-membrane Commun Biol, 2020 Mar siRNA SR511599
BIRC3 IL-1β induces up-regulation of BIRC3, a gene involved in chemoresistance to doxorubicin in breast cancer cells Cancer Lett, 2017 Jan siRNA SR319355
BIRC3 NPD1-mediated stereoselective regulation of BIRC3 expression through cREL is decisive for neural cell survival Cell Death Differ., 2015 Jan siRNA SR300232
Blvra Bliverdin reductase-A improves neurological function in a germinal matrix hemorrhage rat model Neurobiol. Dis., 2017 Dec siRNA SR512469
Braf Identification of Bisindolylmaleimide IX as a potential agent to treat drug-resistant BCR-ABL positive leukemia Oncotarget, 2016 Oct siRNA SR420296
BRAF The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux Autophagy, 2015 Jun siRNA SR300470
BRCA1 Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats J. Biomed. Sci., 2020 May siRNA SR512467
BRCA2 A Functional Analysis of the Unclassified Pro2767Ser BRCA2 Variant Reveals Its Potential Pathogenicity that Acts by Hampering DNA Binding and Homology-Mediated DNA Repair Cancers (Basel) 2019, 2019 Sep siRNA SR423642
BRD2 H2A. Z. 1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs Cell Reports, 2016 Feb siRNA SR419051
BRD4 H2A. Z. 1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs Cell Reports, 2016 Feb siRNA SR422790
BRMS1 MicroRNA-423 enhances the invasiveness of hepatocellular carcinoma via regulation of BRMS1 Am J Transl Res, 2017 Dec siRNA SC207572
BTG3 MicroRNA-519c-3p promotes tumor growth and metastasis of hepatocellular carcinoma by targeting BTG3 Biomed. Pharmacother., 2019 Aug siRNA SR307479
BTRC Role of integrin-linked kinase in regulating the protein stability of the MUC1-C oncoprotein in pancreatic cancer cells Oncogenesis, 2017 Jul siRNA SR305917
C21ORF91 Inherited duplications of PPP2R3B promote naevi and melanoma via a novel C21orf91-driven proliferative phenotype bioRxiv, 2019 Jun siRNA SR310041
C3 C3a Increases VEGF and Decreases PEDF mRNA Levels in Human Retinal Pigment Epithelial Cells BioMed Research International, 2016 Sep siRNA SR300499
C3AR1 Tumor necrosis-initiated complement activation stimulates proliferation of medulloblastoma cells Inflamm. Res., 2015 Jan siRNA SR300500
C87436 NF-κB-Dependent Upregulation of (Pro)Renin Receptor Mediates High NaCl-Induced Apoptosis in Mouse Inner Medullary Collecting Duct Cells Am. J. Physiol., Cell Physiol., 2017 Oct siRNA SR41760
CA12 Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival Sci Rep, 2018 Sep siRNA SR300539
CA9 Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival Sci Rep, 2018 Sep siRNA SR319527
CACNA2D3 CACNA2D3 Enhances the Chemosensitivity of Esophageal Squamous Cell Carcinoma to Cisplatin via Inducing Ca2+-Mediated Apoptosis and Suppressing PI3K/Akt Pathways Front Oncol, 2019 Apr siRNA SR310953
CACNA2D3 Characterization of CACNA2D3 as a putative tumor suppressor gene in the development and progression of nasopharyngeal carcinoma. International journal of cancer, 2014 Mar siRNA SR310953
CADM1 MicroRNA-155-3p promotes breast cancer progression through down-regulating CADM1 Onco Targets Ther, 2019 Sep siRNA SR308445
CALR Dexamethasone-Mediated Upregulation of Calreticulin Inhibits Primary Human Glioblastoma Dispersal Ex Vivo Int J Mol Sci, 2018 Feb siRNA SR300567
Calr Aberrant Calreticulin Expression in Articular Cartilage of Dio2 Deficient Mice PLoS ONE, 2016 May siRNA SR413808
CAMK1D Transcriptome-wide analysis of PGC-1α-binding RNAs identifies genes linked to glucagon metabolic action Proc. Natl. Acad. Sci. U.S.A., 2020 Aug siRNA SR412965
CAMK2A CaMKII inhibition in human primary and pluripotent stem cell-derived chondrocytes modulates effects of TGFβ and BMP through SMAD signaling Osteoarthr. Cartil., 2019 Jan siRNA SR319547
Camk2a Dihydrolipoic Acid Inhibits Lysosomal Rupture and NLRP3 Through Lysosome-Associated Membrane Protein-1/Calcium/Calmodulin-Dependent Protein Kinase II/TAK1 Pathways After Subarachnoid Hemorrhage in Rat Stroke, 2018 Jan siRNA SR500835
CANX N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding Elife, 2018 Jun siRNA SR417891
CANX N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding Elife, 2018 Jun siRNA SR319552
CAPN1 Neuroprotective effect of paeoniflorin on okadaic acid-induced tau hyperphosphorylation via calpain/Akt/GSK-3β pathway in SH-SY5Y cells Brain Res., 2018 Mar siRNA SR300578
CAPN2 Targeting Cellular Calcium Homeostasis to Prevent Cytokine-Mediated Beta Cell Death Sci Rep, 2017 Jul siRNA SR300579
CARD9 Caspase recruitment domain family member 9 expression is a promising biomarker in esophageal squamous cell carcinoma Ann Gastroenterol Surg, 2019 Dec siRNA SR311981
CARD9 The Myeloid LSECtin Is a DAP12-Coupled Receptor That Is Crucial for Inflammatory Response Induced by Ebola Virus Glycoprotein PLoS one, 2016 Mar siRNA SR311981
Casp8 Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4 Cell Rep, 2017 Dec siRNA SR415523
CAV1 Autophagy alleviates hypoxia-induced blood-brain barrier injury via regulation of CLDN5 (claudin 5) Autophagy, 2020 Dec siRNA SR404266
CAV1 Occludin, caveolin-1, and Alix form a multi-protein complex and regulate HIV-1 infection of brain pericytes FASEB J, 2020 Oct siRNA SR319567
CAV1 Identification of BAG3 target proteins in anaplastic thyroid cancer cells by proteomic analysis Oncotarget, 2018 Jan siRNA SR319567
CAV1 Follicular Stimulating Hormone Accelerates Atherogenesis by Increasing Endothelial VCAM-1 Expression Theranostics, 2017 Oct siRNA SR319567
CAV1 CD47 and Nox1 Mediate Dynamic Fluid-Phase Macropinocytosis of Native LDL Antioxid. Redox Signal, 2016 Dec siRNA SR404266
Cav1 Caveolin-1 regulates the expression of tight junction proteins during hyperoxia-induced pulmonary epithelial barrier breakdown Respiratory Research, 2016 May siRNA SR404266
CAV1 SMN affects membrane remodelling and anchoring of the protein synthesis machinery J. Cell. Sci., 2016 Jan siRNA SR300603