Cd4 Rat Monoclonal Antibody [Clone ID: GK1.5]

CAT#: AM00698BT-N

Cd4 rat monoclonal antibody, clone GK1.5, Biotin

Specifications

Product Data

• Clone Name: GK1.5
• Applications: FC, IF, IP
• Recommended Dilution: Immunoflourescence.
  Immunoprecipitation.
  Flow cytometry (1 µg to stain 1.0 x 10e6 cells).
  Useful for studies of T-helper cell functions including blocking of T-helper cell activation.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Lyt-2-negative T-cell clone 243/2.5
• Specificity: Recognizes a determinant designated L3T4 present on T-cell surface with an apparent molecular mass of 52kDa.
• Formulation: 0.01 M PBS, pH 7.4 containing 1 % BSA; 0.09 % Sodium azide
  Label: Biotin
  State: Liquid Ig fraction
• Concentration: 0.5 mg/ml (OD280nm)
• Purification: Protein A chromatography
• Conjugation: Biotin
• Database Link:
  Entrez Gene 12504 Mouse
• Background: CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.
• Synonyms: T-cell surface antigen T4/Leu-3