Luteinizing Hormone beta (LHB) Mouse Monoclonal Antibody [Clone ID: 090-10226]

CAT#: AM00973PU-N

Luteinizing Hormone beta (LHB) mouse monoclonal antibody, clone 090-10226, Purified

Specifications

Product Data

• Clone Name: 090-10226
• Applications: ELISA
• Recommended Dilution: ELISA.
  Recommended Pairs for Sandwich Immunoassay:
  Capture/Detection: AM00973PU-N/AM00975PU-N or AM00972PU-N/AM00973PU-N.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Source: Human Pituitary Gland
• Specificity: This antibody reacts to Luteinizing Hormone (LH).
  Cross-reactivity:
  hCG: < 0.01%
  FSH: > 0.1%
• Formulation: 10mM Phosphate, pH 7.4 +/- 0.2 containing 150mM Sodium Chloride and 0.05% Sodium Azide as preservative.
  State: Purified
  State: Liquid (0.2µm filtered) purified Ig fraction (>90% pure by SDS-PAGE).
• Concentration: lot specific
• Purification: Protein A Chromatography.
• Storage: Store the antibody undiluted at 2-8°C for one week or (in aliquots) at < -40°C for longer.
  Avoid repeated freezing and thawing.
  If aliquoted for long term storage, fill volume should be equal to or greater than 50% of the nominal fill volume of the vial used.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens luteinizing hormone beta polypeptide (LHB)
• Database Link:
  Entrez Gene 3972 Human
• Background: Luteinizing Hormone is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Mutations in the Luteinizing Hormone (LHB) gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
• Synonyms: CGB4; hLHB; LH-B; LSH-B; LSH-beta

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: GnRH signaling pathway, Neuroactive ligand-receptor interaction