CD13 (ANPEP) Mouse Monoclonal Antibody [Clone ID: CVS19]
Specifications
Product Data | |
Clone Name | CVS19 |
Applications | FC, IHC, IP |
Recommended Dilution | Flow cytometry: 1/25-1/200, use 10µl of this working dilution to label 106 cells in 100µl. Immunohistochemistry on frozen sections. Immunoprecipitation. |
Reactivities | Equine |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Equine leucocytes. |
Specificity | This antibody recognises the equine CD13 cell surface antigen. |
Formulation | PBS ontaining 0.09% Sodium azide State: Purified State: Liquid purified IgG |
Concentration | lot specific |
Purification | Affinity chromatography on Protein G |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. In case of precipitate, we recommend microcentrifugation before use. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | alanyl aminopeptidase, membrane |
Background | CD13 also known as Aminopeptidase N is a zinc dependent exopeptidase which cleaves amino acids from the N termini of target proteins including neuropeptides and cytokines. CD13 is expressed on all cells of the myeloid lineage as well as epithelial cells of the intestine, placenta, liver and kidney. CD13 is upregulated in a number of tumour types including lung, melanoma, thyroid and hepatocarcinoma and has been shown to correlate with poor prognosis. CD13 is a crucial molecule in tumour angiogenesis. CD13 is also the receptor for viruses from the coronavirus family. |
Synonyms | Aminopeptidase N, ANPEP, APN, PEPN |
Reference Data |
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