TNFRSF4 Mouse Monoclonal Antibody [Clone ID: 7D6]

CAT#: AM01048FC-N

TNFRSF4 mouse monoclonal antibody, clone 7D6, FITC

Product Images

Lane 1 - Feline CD134 expressing cells Lane 2 - Control cells Lane 3 - Recombinant feline CD134-Fc fusion protein (clone 7D6) used at 1ug/ml

Specifications

Product Data

• Clone Name: 7D6
• Applications: FC, WB
• Recommended Dilution: Flow Cytometry: 1/5; use 10µl of the suggested working dilution to label 1x10e6 cells in 100µl.
• Reactivities: Feline, Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: CHO-derived feline CD134-Fc fusion protein.
• Specificity: This antibody recognizes Feline CD134, otherwise known as OX40.
  The antibody weakly reacts with Human. It does not react with Mouse.
• Formulation: Phosphate buffered saline pH 7.4 containing 0.09% Sodium Azide, 1% BSA
  Label: FITC
  State: Liquid purified Ig fraction
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: lot specific
• Purification: Affinity Chomatography on Protein G
• Conjugation: FITC
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  This product is photosensitive and should be protected from light.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: tumor necrosis factor receptor superfamily member 4
• Database Link:
  Entrez Gene 7293 Human
• Background: CD134 is a 43kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses
  CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.
• Synonyms: TNFRSF4, TXGP1L, ACT35 antigen, OX40L receptor