CD2 Mouse Monoclonal Antibody [Clone ID: CC42]

CAT#: AM01066FC-N

CD2 mouse monoclonal antibody, clone CC42, FITC

Product Images

AM01066FC-N (MOUSE ANTI BOVINE CD2:FITC) staining of bovine peripheral blood lymphocytes.

Specifications

Product Data

• Clone Name: CC42
• Applications: FC
• Recommended Dilution: Flow Cytometry: Neat - 1/10;
  Use 10µl of the suggested working dilution to label 10e6 cells in 100 µl.
• Reactivities: Bovine, Goat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Specificity: This antibody recognises the bovine homologue of human CD2.
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
  Label: FITC
  State: Liquid purified Ig
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.1mg/ml
• Purification: Affinity chromatography on Protein G
• Conjugation: FITC
• Background: CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes.
  CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.
• Synonyms: SRBC, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor
• Note: The antibody inhibits rosetting with SRBC and stains cells in primary and secondary lymphoid organs in patterns consistent with those seen by human CD2 monoclonal antibodies.