Leishmania (gp63) Mouse Monoclonal Antibody [Clone ID: 96-126]
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Specifications
Product Data | |
Clone Name | 96-126 |
Applications | ELISA, IF |
Recommended Dilution | ELISA: 1/2000. Immunofluorescence: 1/500-1/1000. Not suitable for Immunoblotting. |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Recombinant baculovirus expressed Leishmania major gp63 |
Specificity | Recognises the Leishmania major surface protease (gp63), a 63kDa highly conserved protein which is found at high density on many Leishmania species. This antibody recognises living and fixed parasites, but will not bind to denatured or improperly folded recombinant gp63. |
Formulation | State: Ascites State: Lyophilized Ascitic Fluid Stabilizer: None Preservative: None |
Reconstitution Method | Restore with 0.5 ml distilled water. |
Background | The major surface metalloproteinase Gp63 plays an important role in the initial stages of Leishmania/macrophage interactions and the intracellular survival of the parasite. Leishmania is a protozoan of the genus of trypanosome, and the parasite responsible for the disease leishmaniasis. |
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