ZAP70 Mouse Monoclonal Antibody [Clone ID: SBZAP]

CAT#: AM01263FC-S

ZAP70 mouse monoclonal antibody, clone SBZAP, FITC

Specifications

Product Data

• Clone Name: SBZAP
• Recommended Dilution: Flow Cytometry: Membrane permeabilisation is required.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Peptide corresponding to amino acid residues 280-309 of human ZAP-70, conjugated to KLH.
• Specificity: This antibody recognises human ZAP-70.
• Formulation: PBS
  Label: FITC
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: lot specific
• Conjugation: FITC
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
  This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 7535 Human
• Background: ZAP-70 is a 70kDa tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia.
• Synonyms: ZAP-70, ZAP 70, SRK