CD88 / C5R1 Rat Monoclonal Antibody [Clone ID: 10/92]

CAT#: AM01269BT-N

CD88 / C5R1 rat monoclonal antibody, clone 10/92, Biotin

Specifications

Product Data

• Clone Name: 10/92
• Applications: FC
• Recommended Dilution: Flow cytometry: use 10 µl of neat antibody to label 1x10e6 cells in 100 µl.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: RBL-2H3 transfected cells expressing murine C5aR. Cells from immunised Lou/c rats were fused with cells of the X63-Ag8.653 myeloma cell line.
• Specificity: This antibody recognises CD88.
• Formulation: PBS, pH 7.4, containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
  Label: Biotin
  State: Liquid purified IgG
• Concentration: 0.1 mg/ml
• Purification: Affinity chromatography on Protein G
• Conjugation: Biotin
• Background: CD88 is a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR. The CD88 molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes.
• Synonyms: C5a-R, C5aR, C5AR1, Complement Component 5a Receptor 1
• Note: Clone 10/92 does not block the binding of the C5a to murine CD88.