CD79A (202-216) Mouse Monoclonal Antibody [Clone ID: HM57]
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Specifications
Product Data | |
Clone Name | HM57 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 10 µl of neat antibody to label 1x10e6 cells in 100 µl; Membrane permeabilisation is required for this application. |
Reactivities | Bovine, Canine, Chicken, Equine, Guinea Pig, Human, Monkey, Mouse, Porcine, Rabbit, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1 |
Specificity | This antibody recognises an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. |
Formulation | Phosphate buffered saline pH 7.4 containing 0.09% Sodium Azide (NaN3), 1% Bovine Serum Albumin Label: PE State: Lyophilized Ig fraction Label: R. Phycoerythrin (RPE) |
Reconstitution Method | Reconstitute with 0.25 ml distilled water |
Concentration | lot specific |
Purification | Affinity chromatography on Protein G |
Conjugation | PE |
Storage | Store undiluted at 2-8°C. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
Stability | Shelf life: One year from despatch. |
Database Link | |
Background | The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin. |
Synonyms | IGA, MB1, B-Cell marker |
Reference Data |
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