HLA Class I ABC Mouse Monoclonal Antibody [Clone ID: W6/32]

CAT#: AM03005FC-N

HLA Class I ABC mouse monoclonal antibody, clone W6/32, FITC

Product Images

Surface staining of human peripheral blood cells with anti-HLA-class I (W6/32) PE.

Specifications

Product Data

• Clone Name: W6/32
• Applications: FC
• Recommended Dilution: Flow Cytometry (1/300 as starting dilution).
• Reactivities: Bovine, Feline, Human, Primate
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Membrane of Human tonsil cells
• Specificity: The antibody W6/32 recognizes virtually all nucleated human cells. It is a valuable reagent for analysing variations in HLA class I expression in different disease states e.g. liver disease, muscular dystrophy, inflammatory myopathy and other neuromuscular disorders.
  This antibody W6/32 is also suitable as a Positive Control for HLA tissue typing and crossmatching.
• Formulation: Phosphate buffered saline (PBS), pH~7.4
  Label: FITC
  State: Liquid purified IgG fraction
  Preservative: 15 mM Sodium Azide
  Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC.
• Concentration: 1.0 mg/ml
• Conjugation: FITC
• Background: HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta-2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
  MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types.
• Synonyms: MHC class I ABC, HLA Class 2 ABC