CD21 (CR2) Mouse Monoclonal Antibody [Clone ID: LT21]

CAT#: AM03064FC-N

CD21 (CR2) mouse monoclonal antibody, clone LT21, FITC


USD 270.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name LT21
Applications FC
Recommended Dilution Flow Cytometry analysis of Human blood cells using 20 μl reagent / 100 μl of whole blood or 106 cells in a suspension.
Reactivities Bovine, Canine, Human, Porcine
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen IM9 human B-lymphoblastoid cell line
Specificity The antibody LT21 reacts with CD21 (CR2), a 145 kDa transmembrane glycoprotein (complement C3d receptor - C3dR) expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
Formulation PBS
Label: FITC
State: Liquid purified IgG fraction
Preservative: 15 mM Sodium Azide
Label: Conjugated with Fluorescein isothiocyanate under optimum conditions.
Conjugation FITC
Storage Store undiluted at 2-8°C.
DO NOT FREEZE! 
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name complement component 3d receptor 2
Background CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
Synonyms Complement receptor type 2, CR2, C3DR, C3d receptor, EBV Receptor, Dendritic Cell Marker
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.