TSH beta (TSHB) Mouse Monoclonal Antibody [Clone ID: TSH-116]

CAT#: AM03069PU-N

TSH beta (TSHB) mouse monoclonal antibody, clone TSH-116, Aff - Purified

Specifications

Product Data

• Clone Name: TSH-116
• Applications: ELISA, R
• Recommended Dilution: ELISA.
  RIA.
  The antibody TSH-116 is suitable in combination with the antibody TSH-51 (AM03068PU-N) for Immunometric assays in the screening of neonatal hypothyroidism.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Human thyrotropin.
• Specificity: The antibody TSH-116 reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain.
  The TSH-116 reacts with association constant 1.1 x 1011 l/mol.
  Following cross-reactivity expressed as binding of labelled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-116: hTSH (78.9), hCG (20.3), hLH (23.2), hFSH (29.9).
• Formulation: PBS, pH 7.4 with 15 mM sodium azide as preservative.
  State: Aff - Purified
  State: Liquid purified IgG fraction (> 95% pure by SDS-PAGE).
• Concentration: lot specific
• Purification: Protein A affinity chromatography.
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens thyroid stimulating hormone beta (TSHB), transcript variant 1
• Database Link:
  Entrez Gene 7252 Human
• Background: Thyrotropin (hTSH) promotes the growth of the thyroid gland in the neck and stimulates it to produce more thyroid hormones. hTSH is composed of two subunits - alpha and beta.
• Synonyms: Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH, TSHB, TSH beta

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Autoimmune thyroid disease, Neuroactive ligand-receptor interaction