CD62L (SELL) Mouse Monoclonal Antibody [Clone ID: LT-TD180]

CAT#: AM03090AC-N

CD62L (SELL) mouse monoclonal antibody, clone LT-TD180, APC

Product Images

Surface staining of human peripheral blood cells with anti-CD62L (LT-TD180) APC.

Specifications

Product Data

• Clone Name: LT-TD180
• Applications: FC
• Recommended Dilution: Flow cytometry: 10 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension.
  The content of a vial (1 ml) is sufficient for 100 tests.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Peripheral blood leukocytes
• Specificity: The antibody LT-TD180 reacts with CD62L (L-selectin), a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.
• Formulation: Phosphate buffered saline (PBS) containing 15 mM sodium azide
  Label: APC
  State: Liquid Ig fraction
  Label: Conjugated with cross-linked Allophycocyanin under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
• Conjugation: APC
• Storage: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens selectin L (SELL), transcript variant 1
• Database Link:
  Entrez Gene 6402 Human
• Background: CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
• Synonyms: SELL, LNHR, LYAM1, Leu-8, TQ1, gp90-MEL, LECAM1, LAM-1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)