HLA Class II DR Mouse Monoclonal Antibody [Clone ID: MEM-12]
Specifications
Product Data | |
Clone Name | MEM-12 |
Applications | FC |
Recommended Dilution | Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Thymocyte membrane |
Specificity | This antibody recognizes common epitope on human HLA-DR which is dependent on the association of alpha and beta chains. DR is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages). |
Formulation | Phosphate buffered saline (PBS) Label: PerCP State: Liquid purified Ig fraction Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) Preservative: 15 mM sodium azide Label: Conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. |
Conjugation | PerCP |
Background | HLA-DR, a member of MHC class II glycoproteins, that bind intracellularly processed peptides and present them to the Th cells, is composed of 36 kDa alpha chain and 27 kDa beta chain, both anchored in the plasma membrane. Together with other MHC II molecules HLA-DR plays a central role in the immune system. |
Synonyms | HLA-DR, HLA class II histocompatibility |
Reference Data |
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