CD69 Mouse Monoclonal Antibody [Clone ID: FN50]
Specifications
Product Data | |
Clone Name | FN50 |
Applications | FC |
Recommended Dilution | Flow cytometry (use 10 µl reagent / 100 µl of whole blood or 10e6 cells in a suspension). The content of a vial (1 ml) is sufficient for 100 tests. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Anti-µ-stimulated human B lymphocytes |
Specificity | The antibody recognizes CD69, an lymphocyte early activation marker detected as a 53 kDa band under nonreducing and as 29 + 32 kDa double band under reducing SDS-PAGE conditions. |
Formulation | Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent. Label: APC State: Liquid purified Ig fraction Label: Conjugated with cross-linked Allophycocyanin under optimum conditions.The conjugate is purified by size-exclusion chromatography and adjusted for direct use |
Conjugation | APC |
Storage | Store the antibody at 2 - 8 °C. DO NOT FREEZE! Centrifuge vial before opening. This product is photosensitive and should be protected from light. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets; it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy. |
Synonyms | GP32/28, Leu-23, MLR-3, EA1, BL-AC/P26, AIM |
Reference Data |
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