CD69 Mouse Monoclonal Antibody [Clone ID: FN50]

CAT#: AM03132PU-N

CD69 mouse monoclonal antibody, clone FN50, Aff - Purified


USD 220.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name FN50
Applications FC, FN, IHC, WB
Recommended Dilution Flow Cytometry: 5 µg/ml.
Western blot: 53 kDa, under reducing conditions it shows two bands of 29 and 32 kDa.
Immunohistochemistry on Frozen Sections.
Functional Assay: When stimulating peripheral blood T cells, FN50 antibody together with TPA synergistically increases cell volume and RNA/DNA synthesis. Addition of FN50 to stimulated peripheral blood B cells has similar, but weaker effect.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Anti-µ-stimulated human B lymphocytes
Specificity The antibody recognizes CD69, an lymphocyte early activation marker detected as a 53 kDa band under nonreducing and as 29 + 32 kDa double band under reducing SDS-PAGE conditions.
Formulation PBS, pH~7.4
State: Aff - Purified
State: Liquid purified Ig fraction (> 95% by SDS-PAGE)
Preservative: 15 mM Sodium Azide
Concentration lot specific
Purification Affinity Chromatography on Protein A
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
Stability Shelf life: one year from despatch.
Background CD69 (C-type lectin domain family 2 C, CLEC2C, also known as AIM) is one of the earliest inducible cell surface molecules acquired during leukocyte activation. This glycoprotein serves as a lectin-type receptor in lymphocytes, NK cells and platelets; it is involved in lymphocyte proliferation. CD69 expression is counteracted on T cells in the AIDS stage of HIV infection, and may be also predictive for clinical response to chemoimmunotherapy.
Synonyms GP32/28, Leu-23, MLR-3, EA1, BL-AC/P26, AIM
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.