ICAM1 Mouse Monoclonal Antibody [Clone ID: 1H4]

CAT#: AM03205PP-N

ICAM1 mouse monoclonal antibody, clone 1H4, PerCP


USD 300.00

2 Weeks*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name 1H4
Applications FC
Recommended Dilution Flow Cytometry analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension.
The content of a vial (1 ml) is sufficient for 100 tests.
Reactivities Human
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Raji cells and spleen cells fused with NS1 cells
Specificity The antibody 1H4 reacts with CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus) expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells; the expression of CD54 is upregulated by activation.
Formulation Phosphate buffered saline (PBS)
Label: PerCP
State: Liquid purified Ig fraction
Stabilizer: 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA)
Preservative: 15 mM sodium azide
Label: Conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Conjugation PerCP
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
This products is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Gene Name intercellular adhesion molecule 1
Background CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.
Synonyms ICAM-1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.