Il2 Rat Monoclonal Antibody [Clone ID: I2-C7]

CAT#: AM05018PU-N

Il2 rat monoclonal antibody, clone I2-C7, Azide Free


USD 380.00

2 Weeks*

Size
    • 200 ug

Product Images

Specifications

Product Data
Clone Name I2-C7
Applications FN
Recommended Dilution A 1:50 dilution will block 50 - 70% of CTLL proliferative response to 5% Con A sup as a source for mouse IL-2. This antibody will also block 50 - 70% of MLR or T cell proliferation to KLH
Reactivities Mouse
Host Rat
Isotype IgG
Clonality Monoclonal
Immunogen Mouse IL-2 purified from Con A activated T cell supernatant
Specificity This antibody reacts to IL-2. Does not cross react with rat or human IL-2.
Formulation PBS
State: Azide Free
State: Lyophilized purified Ig
Reconstitution Method Restore with 0.2ml water. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Concentration lot specific
Purification Protein A/S-Sepharose
Storage Prior to reconstitution store at 2-8°C.
Following reconstitution store the antibody at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.
Synonyms IL-2, TCGF
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.