Rabies Virus Mouse Monoclonal Antibody [Clone ID: RV1C5]

CAT#: AM05059PU-N

Rabies Virus mouse monoclonal antibody, clone RV1C5, Purified

Specifications

Product Data

• Clone Name: RV1C5
• Applications: ELISA, IF, IHC, NEUT
• Recommended Dilution: Detection of Rabies and Rabies related virus.
  Immunohistochemistry on Paraffin Sections.
  Indirect ELISA: 1.5x10⁶.
  Immunofluorescence: Specific Titer > 1x10³.
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Purified Rabies virus
• Specificity: Rabies Virus antibody reacts with a glycoprotein of Rabies virus. More than 20 different strains from 4 serogroups, including CVS, Lagosbat, Mokola, Duwenhage were positive in neutralization reaction.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction (>95% pure by SDS-PAGE).
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Protein G Chromatography
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Background: Rabies virus (Neurotropic lyssavirus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumblike glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Virus infectivity is destroyed by lipid solvents. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.