RYK Mouse Monoclonal Antibody [Clone ID: F35 P7 D7 F5]

CAT#: AM05388PU-N

RYK mouse monoclonal antibody, clone F35 P7 D7 F5, Purified

Product Images

Western blot using RYK antibody on HCT116 cell lysates.

Specifications

Product Data

• Clone Name: F35 P7 D7 F5
• Applications: WB
• Recommended Dilution: Western Blot: 1-5 µg/ml.
  Positive Control: HCT116 cell lysates.
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the human RYK protein and mouse myeloma Ag8563 cells. Sequence common in human, mouse and rat.
• Specificity: This antibody reacts to Receptor-Like Tyrosine Kinase.
• Formulation: Phosphate buffered saline with 0.08% sodium azide
  State: Purified
  State: Liquid purified Ig
• Concentration: Lot specific
• Database Link:
  Entrez Gene 6259 Human
• Background: RYK (Receptor like Tyrosine kinase 1) is in the Tyrosine family of receptor kinases. It is found in the plasma membrane of heart, prostate and kidney cells. RYK contains 604 amino acids and it contains one WIF domain. It functions as a potential growth factor receptor protein tyrosine kinase. RYK are divergent from those of other classic receptor tyrosine kinases. It is an orphan receptor that contains a catalytically inactive tyrosine kinase related domain. RYK is expressed in nestin positive progenitor cells and neurons, and in a certain population of oligodendrocytes, O2A progenitor cells, and type 2 astrocytes in developing CNS.
• Synonyms: JTK5A