IL6 Rat Monoclonal Antibody [Clone ID: MQ2-39C3]

CAT#: AM05404PU-N

IL6 rat monoclonal antibody, clone MQ2-39C3, Purified


USD 580.00

5 Days*

Size
    • 500 ug

Product Images

Specifications

Product Data
Clone Name MQ2-39C3
Applications ELISA
Recommended Dilution ELISA.
Reactivities Human
Host Rat
Isotype IgG2a
Clonality Monoclonal
Specificity This antibody recognises interleukin 6.
Formulation Borate buffered saline
State: Purified
State: Liquid purified IgG
Concentration lot specific
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name interleukin 6
Background Interleukin 6 (IL6) is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass.

IL6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL6 appears to interact with IL2 in the proliferation of T lymphocytes. IL6 potentiates the proliferative effect of IL3 on multipotential hematopoietic progenitors.
Synonyms IL-6, Interferon beta-2, IFNB2, B-cell stimulatory factor 2, BSF-2, CDF
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.