Itgax Hamster Monoclonal Antibody [Clone ID: N418]

CAT#: AM05514PU-T

Itgax hamster monoclonal antibody, clone N418, Purified


USD 190.00

5 Days*

Size
    • 25 ug

Product Images

Specifications

Product Data
Clone Name N418
Applications FC, IHC, IP
Recommended Dilution Immunohistochemistry on Frozen Sections.
Immunoprecipitation.
Flow Cytometry: Use 10 µl of 1/25-1/100 diluted antibody to label 1x106 cells in 100 µl.
Reactivities Mouse
Host Hamster
Isotype IgG
Clonality Monoclonal
Immunogen Mouse spleen dendritic cells.
Specificity This antibody recognises the murine homologue of Human CD11c, which is a 150/90kD member of the beta 2 integrin family. In mice, CD11c is primarily expressed by dendritic cells.
Clone N418 has been reported to enhance antigen specific responses when used to target dendritic cells in vivo. (Ref.3)
Formulation PBS, pH 7.4 containing 0.09% Sodium Azide as preservative.
State: Purified
State: Liquid purified IgG fraction
Concentration 1.0 mg/ml
Purification Affinity Chromatography on Protein G.
Background CD11c (integrin alpha X chain protein) combines with the beta 2 chain (ITGB2) to form a leukocyte specific integrin referred to as inactivated C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. The CD11c antigen is a marker for hairy cell leukaemia.
Synonyms ITGAX, Integrin alpha-X, Leu M5
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.