HMB45 Mouse Monoclonal Antibody [Clone ID: HMB45]

CAT#: AM05542SU-N

HMB45 mouse monoclonal antibody, clone HMB45

Specifications

Product Data

• Clone Name: HMB45
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on frozen sections: 1/40.
  Immunohistochemistry on paraffin sections: 1/40; This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
  Histology Positive Control Tissue: Melanoma.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Extract of pigmented melanoma metastases from lymph nodes.
• Specificity: This antibody recognises the HMB-45 antigen, an intracytoplasmic antigen expressed by the majority of melanomas and with other tumours demonstrating melanocytic differentiation. Tumours of lymphoid, epithelial, glial and mesenchymal origin are negative. Normal adult melanocytes do not label with this antibody, although fetal and neonatal melanocytes stain variably.
  
  
• Formulation: Phosphate buffered saline containing 0.09% Sodium Azide, 1% Bovine Serum Albumin
  State: Liquid purified IgG
• Synonyms: HMB45 Melanoma Marker