Klrd1 Rat Monoclonal Antibody [Clone ID: 18d3]
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Specifications
Product Data | |
Clone Name | 18d3 |
Applications | FC |
Recommended Dilution | Flow Cytometry: Use 10 µl of 1/50-1/200 diluted antibody to labell 10e6 cells in 100 µl. |
Reactivities | Mouse |
Host | Rat |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | CHO cells transfected with B6 allele of CD94 |
Specificity | This antibody recognises CD94. |
Formulation | Phosphate buffered saline pH 7.4 containing 0.09% Sodium Azide as preservative State: Purified State: Liquid purified IgG fraction |
Concentration | 1.0 mg/ml |
Purification | Affinity Chromatography on Protein G |
Database Link | |
Background | CD94 is a 70kD cell surface glycoprotein expressed primarily by mouse natural killer (NK) cells. The murine CD94 molecule forms heterodimers with NKG2A, C or E subunits to form the CD94/NKG2 receptor. In mice the CD94/NKG2 receptor recognises Qa-1 b, a non-classical MHC class 1 molecule. CD94/NKG2 receptors may play an important role in self-tolerance of NK cells during fetal and neonatal life. N.B. Recent reports suggest that DBA/2J mice do not express cell surface CD94/NKG2A receptors. |
Synonyms | KLRD1, KP43, NK cell receptor |
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