CD65s Mouse Monoclonal Antibody [Clone ID: VIM-2]

CAT#: AM05590FC-N

CD65s mouse monoclonal antibody, clone VIM-2, FITC

Specifications

Product Data

• Clone Name: VIM-2
• Applications: FC
• Recommended Dilution: Flow Cytometry: 1/10.
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: THP1 (human acute monocytic leukaemia cells)
• Specificity: This antibody selectively recognises the sialylated form of human CD65, known as CD65s (VIM-2 antigen).
  Cross-linking of the CD65s antigen using clone VIM-2, has been shown to induce phagocyte cytoplasmic calcium flux, oxidative burst and degranulation.
• Formulation: Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide (NaN3), 1% Bovine Serum Albumin
  Label: FITC
  State: Liquid purified IgM
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.1mg/ml
• Purification: Ammonium sulphate precipitation
• Conjugation: FITC
• Background: CD65 is a leucocyte carbohydrate antigen expressed by granulocytes, monocytes and leukaemic cells of myelomonocytic lineage.
  CD65s is aberrantly expressed on some acute myeloid leukaemias (AML) and clone VIM-2 has been reliably used as a marker for distinguishing between mature and undifferentiated AML. During normal myelopoiesis, expression of CD65s follows the disappearance of the progenitor antigen CD34.
• Synonyms: CDw65