SLC44A1 Mouse Monoclonal Antibody [Clone ID: VIM-15b]

CAT#: AM05591RP-N

SLC44A1 mouse monoclonal antibody, clone VIM-15b, PE

Specifications

Product Data

• Clone Name: VIM-15b
• Applications: FC
• Recommended Dilution: Flow Cytometry: 1/10.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: MV4-11 acute monocyte leukaemia cells.
• Specificity: This antibody is specific for the C-terminal variant of human CDw92 (isoform 3), also known as CTL1. Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10.
• Formulation: Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide (NaN3) and 1% Bovine Serum Albumin
  Label: PE
  State: Lyophilized purified IgG
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Reconstitute with 1.0ml distilled water
• Concentration: 0,1 mg/ml
• Purification: Affinity chromatography on Protein G
• Conjugation: PE
• Database Link:
  Entrez Gene 23446 Human
• Background: CDw92 is a 70kDa multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells.
  CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine.
• Synonyms: CDw92, CTL1