Siglec 7 (SIGLEC7) Mouse Monoclonal Antibody [Clone ID: 5-386]

CAT#: AM05592RP-N

Siglec 7 (SIGLEC7) mouse monoclonal antibody, clone 5-386, PE

Specifications

Product Data

• Clone Name: 5-386
• Applications: FC
• Recommended Dilution: Flow Cytometry.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Monocyte-derived dendritic cells
• Specificity: This antibody is specific for CDw328.
• Formulation: Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide (NaN3) and 1% Bovine Serum Albumin
  Label: PE
  State: Lyophilised purified IgG
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Reconstitute with 1.0ml distilled water
• Concentration: 0,1 mg/ml
• Purification: Affinity chromatography on Protein G
• Conjugation: PE
• Database Link:
  Entrez Gene 27036 Human
• Background: CDw328 is a type I transmembrane glycoprotein and member of the Siglec (sialic acid binding Ig-like lectin) family, designated Siglec-7, originally identified as an inhibitory NK cell receptor (NKR) and negative regulator of NK activation, attributed to ITIM recruitment of SHP-1 phosphatase.
  CDw328 is expressed predominantly by natural killer cells (NK) and to a lesser extent by monocytes and granulocytes and, like Siglec-5 (CD170), has been shown to bind to sialylated ligands of targets through recognition of sialic acid in both the alpha-2,3- and alpha-2,6- glycosidic linkage.
• Synonyms: Siglec-7, QA79 membrane protein, p75, D-siglec, CDw328, AIRM1