SIRPG Mouse Monoclonal Antibody [Clone ID: OX119]

CAT#: AM05600RP-N

SIRPG mouse monoclonal antibody, clone OX119, PE

Specifications

Product Data

• Clone Name: OX119
• Applications: FC
• Recommended Dilution: Flow Cytometry: 1/10.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant SIRPgamma.CD4.
• Specificity: This antibody recognises SIRP gamma, a 55kD signal regulatory protein which is a member of the immunoglobulin gene superfamily.
• Formulation: Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide (NaN3) and 1% Bovine Serum Albumin
  Label: PE
  State: Lyophilised purified IgG
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Reconstitute with 1.0ml distilled water
• Concentration: 0,1 mg/ml
• Purification: Affinity chromatography on Protein G
• Conjugation: PE
• Database Link:
  Entrez Gene 55423 Human
• Background: SIRP gamma, also known as CD172g, is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. It is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.
• Synonyms: SIRP-beta-2, SIRP-b2, SIRPB2, SIRP gamma