PD L2 (PDCD1LG2) Mouse Monoclonal Antibody [Clone ID: MIH14]
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Specifications
Product Data | |
Clone Name | MIH14 |
Applications | C, FC |
Recommended Dilution | IHC, FC |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human B7-DC transfected L cells |
Specificity | This antibody detects CD273, also known as B7-DC and Programmed Death Ligand 2 (PD-L2). CD273 is a 42kD member of the immunoglobulin receptor superfamily, and is a ligand for CD279 (PD-1). CD273 is primarily expressed on dendritic cells, and its expressio |
Formulation | Phosphate buffered saline pH 7.4, 0.09% Sodium Azide (NaN3) |
Concentration | 1,0 mg/ml |
Purification | Affinity chromatography on Protein G |
Predicted Protein Size | 30.8 kDa |
Gene Name | programmed cell death 1 ligand 2 |
Database Link | |
Background | CD273 functions to inhibit T-cell proliferation by blocking cell cycle progression and cytokine production, and is particularly important in the maintenance of self tolerance. |
Synonyms | B7-DC; B7DC; bA574F11.2; Btdc; CD273; MGC142238; MGC142240; PD-L2; PDCD1L2; PDL2 |
Reference Data | |
Protein Families | Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs) |
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