Slc3a2 Rat Monoclonal Antibody [Clone ID: H202-529.4.1.4]

CAT#: AM05637PU-N

Slc3a2 rat monoclonal antibody, clone H202-529.4.1.4, Purified

Product Images

Staining of mouse peripheral blood lymphocytes with RAT ANTI MOUSE CD98.

Specifications

Product Data

• Clone Name: H202-529.4.1.4
• Applications: FC
• Recommended Dilution: Flow Cytometry: 1/20 - 1/200; Use 10 µl of the suggested working dilution to label 1x10e6 cells in 100 µl.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Thymic epithelial cells from mouse
• Specificity: This antibody recognises CD98 (also known as 4F2 and SLC3A2), a type II transmembrane glycoprotein which associates with members of the L-type amino transporter family to form a heterodimeric complex.
• Formulation: Phosphate buffered saline pH 7.4 containing 0.09% Sodium Azide (NaN3)
  State: Purified
  State: Liquid Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography on Protein G
• Database Link:
  Entrez Gene 17254 Mouse
• Background: CD98 constitutes the heavy chain of the complex and is required for the surface expression and basolateral localization of the amino acid transporter complex in polarized epithelial cells. The CD98 heavy chain also interacts with beta 1 integrins and regulates their activation through the cytoplasmic domains and transmembrane regions. Studies suggest that overexpression of CD98 may contribute to cell growth and survival by regulating integrin signalling, and therefore may play an important role in tumorigenesis.
• Synonyms: 4F2hc, MDU1