CD56 (NCAM1) Mouse Monoclonal Antibody [Clone ID: 123C3]

CAT#: AM05639FC-N

CD56 (NCAM1) mouse monoclonal antibody, clone 123C3, FITC

Product Images

Staining of hamster peripheral blood lymphocytes with MOUSE ANTI HUMAN CD56: FITC.

Specifications

Product Data

• Clone Name: 123C3
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of Neat-1/10 diluted antibody to label 1x10⁶ cells in 100 µl.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Small cell lung carcinoma
• Specificity: This antibody recognises neural cell adhesion molecule (NCAM), otherwise known as CD56.
• Formulation: PBS, pH 7.4
  Label: FITC
  State: Liquid purified IgG fraction
  Stabilizer: 1% BSA
  Preservative: 0.09% Sodium Azide
  Label: Fluorescein Isothiocyanate Isomer 1
  Absorption emission: 490 nm / 525 nm
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein G
• Conjugation: FITC
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  This product is photosensitive and should be preotected from light.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Database Link:
  Entrez Gene 4684 Human
• Background: The CD56 molecule is a cell surface glycoprotein which is expressed on neuroendocrine cells, natural killer cells and a subset of T cells in the peripheral blood. Three main isoforms of CD56 exist. Neurons express the largest 180kD form, while haemopoietic cells express the 140kD isoform. Antibodies produced by clone 123C3 recognise the 140 and 180kD isoforms of the CD56 protein.
  In neuronal tissues, CD56 mediates homophilic and heterophilic adhesion and is implicated in neural development. Studies suggest that CD56 is also expressed on thyroid follicular epithelium and may play a role in autoimmune disease of the thyroid. CD56 is expressed in a range of tumours including tumours of the lung, neural derived malignancies and natural killer cell lymphomas.
• Synonyms: NCAM-1, N-CAM-1, NCAM