Cd8a Rat Monoclonal Antibody [Clone ID: 53-6.7]

CAT#: AM05640FC-N

Cd8a rat monoclonal antibody, clone 53-6.7, FITC

Specifications

Product Data

• Clone Name: 53-6.7
• Applications: FC
• Recommended Dilution: Flow Cytometry.
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Mouse thymus or spleen.
• Specificity: This antibody detects CD8a, the alpha chain of the CD8 antigen. CD8 is expressed on T-cells, and exists either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain.
  This antibody Clone 53-6.7 has been reported to block antigen presentation via MHC class I and inhibit T cell responses to IL-2. This antibody has also been used for depletion of CD8a+ cells.
• Formulation: PBS, pH 7.2 containing 0.09% Sodium Azide as preservative and 1% BSA as stabilizer.
  Label: FITC
  State: Liquid purified IgG fraction.
  Label: Fluorescein Isothiocyanate Isomer 1
• Concentration: 0.5mg/ml
• Purification: Affinity Chromatography on Protein G.
• Conjugation: FITC
• Database Link:
  Entrez Gene 12525 Mouse
• Background: CD8 functions as a co-receptor with the T-cell receptor and mediates efficient cell to cell interactions within the immune system. The CD8 alpha chain specifically binds to class I MHC molecules.
• Synonyms: CD8 alpha chain, CD8A, MAL