Cd14 Mouse Monoclonal Antibody [Clone ID: biG57]

CAT#: AM05665RP-N

Cd14 mouse monoclonal antibody, clone biG57, PE

Product Images

Staining of Mouse peripheral blood monocytes with Mouse anti Mouse CD14 -PE conjugated Antibody Cat.-No AM05665RP-N.

Specifications

Product Data

• Clone Name: biG57
• Applications: FC
• Recommended Dilution: Flow Cytometry: Use 10 µl of neat Antibody to label 1x10⁶ cells in 100 µl.
• Reactivities: Mouse
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant Mouse CD14
• Specificity: This Monoclonal antibody recognizes Mouse CD14.
  Antibodies produced by biG 57 do not inhibit the binding of CD14.
• Formulation: PBS, pH 7.4
  Label: PE
  State: Lyophilised purified IgG fraction
  Stabilizer: 1% BSA
  Preservative: 0.09% Sodium Azide
  Label: R. Phycoerythrin (RPE)
• Reconstitution Method: Restore with 1.0 ml distilled water
• Purification: Affinity Chromatography on Protein G
• Conjugation: PE
• Gene Name: CD14 antigen
• Database Link:
  Entrez Gene 12475 Mouse
• Background: CD14 is a 55kD a glycophosphoinositol-linked cell surface protein that also exists in a soluble form. Expression of CD14 is restricted to the myeloid lineage and is predominantly expressed on peripheral blood monocytes, weakly expressed on granulocytes and absent on myeloid progenitors. The CD14 molecule acts as a pattern recognition receptor, which binds lipopolysaccharide (LPS) and other microbial products such as lipoteichoic acid, lipoproteins and peptidoglycan. Binding of LPS to CD14 mediates the innate immune response to LPS and requires the Toll-like receptor-4 (TLR4)/MD-2 complex for effective signalling.
• Synonyms: CD14