CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: CBR-p150/4G1]

CAT#: AM05669AF-N

CD11c (ITGAX) mouse monoclonal antibody, clone CBR-p150/4G1, Azide Free


USD 670.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name CBR-p150/4G1
Applications FC, FN, IHC
Recommended Dilution Flow Cytometry.
Immunohistochemistry on frozen sections: 5 - 10µg/ml.
Functional Assays.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant human CD11c
Specificity This antibody specifically recognises CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150,95. Clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. This antibody does not recognise CD11a, CD11b or CD18.
Formulation Phosphate buffered saline
State: Azide Free
State: Liquid purified IgG
Concentration 1.0mg/ml
Purification Affinity chromatography on Protein A
Background CD11c is a 150kDa type I transmembrane protein and member of the integrin alpha chain family, expressed by monocytes, macrophages, granulocytes and NK cells, and is a marker for hairy cell leukaemia cells. CD11c combines with the CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, acts as a mediator of leukocyte adherence to endothelium, and binds to the ligands CD54 (ICAM1), iC3b and fibrinogen.
Synonyms ITGAX, Integrin alpha-X, Leu M5
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.