CD11c (ITGAX) Mouse Monoclonal Antibody [Clone ID: CBR-p150/4G1]

CAT#: AM05669AF-N

CD11c (ITGAX) mouse monoclonal antibody, clone CBR-p150/4G1, Azide Free

Specifications

Product Data

• Clone Name: CBR-p150/4G1
• Applications: FC, FN, IHC
• Recommended Dilution: Flow Cytometry.
  Immunohistochemistry on frozen sections: 5 - 10µg/ml.
  Functional Assays.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant human CD11c
• Specificity: This antibody specifically recognises CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150,95. Clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. This antibody does not recognise CD11a, CD11b or CD18.
• Formulation: Phosphate buffered saline
  State: Azide Free
  State: Liquid purified IgG
• Concentration: 1.0mg/ml
• Purification: Affinity chromatography on Protein A
• Database Link:
  Entrez Gene 3687 Human
• Background: CD11c is a 150kDa type I transmembrane protein and member of the integrin alpha chain family, expressed by monocytes, macrophages, granulocytes and NK cells, and is a marker for hairy cell leukaemia cells. CD11c combines with the CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, acts as a mediator of leukocyte adherence to endothelium, and binds to the ligands CD54 (ICAM1), iC3b and fibrinogen.
• Synonyms: ITGAX, Integrin alpha-X, Leu M5