IL8 (CXCL8) Mouse Monoclonal Antibody [Clone ID: NAPII]
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Specifications
Product Data | |
Clone Name | NAPII |
Recommended Dilution | Flow Cytometry. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Recombinant IL-8 |
Specificity | This antibody is specific for IL-8 (interleukin-8). |
Formulation | Tris - NaCl pH7.4 containing 0.02% Sodium Azide (NaN3) and 1% Bovine Serum Albumin Label: FITC State: Liquid purified IgG |
Purification | Affinity chromatography on Protein G |
Conjugation | FITC |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. |
Stability | Shelf life: one year from despatch. |
Gene Name | C-X-C motif chemokine ligand 8 |
Database Link | |
Background | IL-8 is a pro-inflammatory CXC chemokine designated CXCL8, secreted by endothelial cells and monocytes, which acts as a major chemoattractant for neutrophils, T cells and basophils. IL-8, first isolated from osteosarcoma cells, contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors. Cancer studies have demonstrated a role for IL-8 in the angiogenesis and growth of tumours. Previous nomenclature for IL-8 includes neutrophil activating protein 1(NAP-1), granulocyte chemotactic protein 1 (GCP-1), monocyte-derived neutrophil-activating peptide (MONAP) and protein 3-10C. |
Synonyms | CXCL8, Protein 3-10C, Emoctakin, GCP1, MDNCF, MONAP, NAP1 |
Reference Data |
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