Il1a Mouse Monoclonal Antibody [Clone ID: Flo1]
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Specifications
Product Data | |
Clone Name | Flo1 |
Applications | ELISA, FN |
Recommended Dilution | ELISA. Functional Assays: 50µg/ml. |
Reactivities | Mouse |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Recombinant mouse IL-1 alpha |
Specificity | This antibody specifically recognises interleukin-1 alpha (IL-1 alpha). Clone Flo1 can be used in functional studies to neutralize the activity of 125pg/ml of recombinant mouse IL-1 alpha by 95%, as tested using mouse D10(N4)M T-helper cells. |
Formulation | Phosphate buffered saline State: Azide Free State: Liquid purified IgG |
Concentration | 1.0mg/ml |
Purification | Affinity chromatography |
Gene Name | Mus musculus interleukin 1 alpha (Il1a) |
Database Link | |
Background | IL-1 alpha is a pleiotropic pro-inflammatory cytokine and member of the IL-1 superfamily, secreted by activated macrophages and monocytes, which mediates a wide range of immune and inflammatory responses. IL-1 alpha and closely related IL-1 beta, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a. |
Synonyms | IL-1 alpha, IL1F1, IL1A, Hematopoietin-1 |
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