CD8A Rat Monoclonal Antibody [Clone ID: YTC182.20]

CAT#: AM05690PU-N

CD8A rat monoclonal antibody, clone YTC182.20, Purified


USD 475.00

5 Days*

Size
    • 200 ug

Product Images

Specifications

Product Data
Clone Name YTC182.20
Applications FC, IHC
Recommended Dilution Immunohistochemistry on frozen sections.
Flow Cytometry: 1/100 - 1/200.
Reactivities Human, Monkey
Host Rat
Isotype IgG2b
Clonality Monoclonal
Immunogen Mouse L cells transfected with human CD8 gene
Specificity This antibody recognises the CD8 cell surface antigen, a 30/32kD glycoprotein expressed by the cytotoxic/suppressor subset of T lymphocytes, and more weakly by NK cells.
Formulation Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide
State: Purified
State: Liquid purified IgG
Concentration lot specific
Purification Affinity chromatography on Protein G
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.
Synonyms CD8 alpha chain, CD8A, MAL
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.