IL4 Mouse Monoclonal Antibody [Clone ID: CC303]

CAT#: AM05868RP-N

IL4 mouse monoclonal antibody, clone CC303, PE


USD 795.00

5 Days*

Size
    • 100 Tests

Product Images

Specifications

Product Data
Clone Name CC303
Recommended Dilution Flow Cytometry: 1/5.
Reactivities Bovine, Canine, Goat, Porcine, Sheep, Mustelid
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Specificity This antibody recognises bovine interleukin 4.
Formulation Phosphate buffered saline pH7.4 containing 0.09% Sodium Azide, 1% Bovine Serum Albumin
Label: PE
State: Lyophilised purified IgG
Label: R. Phycoerythrin (RPE)
Reconstitution Method Reconstitute with 1 ml distilled water
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation PE
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Background IL4 is a pleiotropic cytokine produced by activated T cells, mast cells and basophils. It is a ligand for Interleukin 4 receptor. The Interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. IL4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL4, IL5, IL10 and IL13, which tend to favor a humoral immune response while suppressing a cell mediated immune response controlled by Th1 cells. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. The second is regulating IgE and IgG1 production by B cells. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Synonyms IL-4, BSF1, Lymphocyte stimulatory factor 1, Binetrakin, Pitrakinra
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.