CD172a / SIRPA Mouse Monoclonal Antibody [Clone ID: BL1H7]

CAT#: AM05885FC-N

CD172a / SIRPA mouse monoclonal antibody, clone BL1H7, FITC


USD 705.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name BL1H7
Applications FC
Recommended Dilution Flow Cytometry: Use 10 µl of neat-1/10 diluted antibody to label 1x106 cells in 100 µl.
Reactivities Porcine
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Porcine alveolar macrophages
Specificity This antibody is specific for the CD172a antigen, also known as SWC3, which is a member of the signal regulatory protein (SIRP) family. CD172a is expressed by granulocytes, monocytes and macrophages.
Formulation PBS
Label: FITC
State: Liquid purified IgG fraction
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.1 mg/ml
Purification Affinity Chromatography on Protein G
Conjugation FITC
Background Protein tyrosine phosphatases (PTPases) SHP1 and SHP2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPa (1),SHPS1 , MyD1, BIT and p84. SIRPa is a new gene family containing at least fifteen members. SIRPa is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP2. SIRPa has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.
Synonyms SHP substrate 1, SHPS-1, Sirp-alpha-2, Sirp-alpha-3, MyD-1 antigen, p84, BIT, MFR, MYD1, PTPNS1, SHPS1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.