Siglec1 Rat Monoclonal Antibody [Clone ID: 3D6.112]

CAT#: AM05902FC-N

Siglec1 rat monoclonal antibody, clone 3D6.112, FITC


USD 505.00

5 Days*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name 3D6.112
Applications FC
Recommended Dilution Flow Cytometry: Neat-1/5 (The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors).
Reactivities Mouse
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen Purified Sialoadhesin.
Spleen cells from an immunised AO rat were fused with the cells of the Y3 rat myeloma cell line.
Specificity This antibody recognizes Mouse CD169, a sialic acid binding site of sialoadhesin.
Formulation PBS
Label: FITC
State: Liquid purified IgG fraction from Tissue Culture Supernatant
Stabilizer: 1% BSA
Preservative: 0.09% Sodium Azide
Label: Fluorescein Isothiocyanate Isomer 1
Concentration 0.1 mg/ml
Purification Affinity Chromatography on Protein G
Conjugation FITC
Background Two families of mammalian lectin like adhesion molecules have been shown to bind glycoconjugate ligands in a sialic acid dependent manner: the selectins and the sialoadhesins. The sialoadhesin family has 4 members: CD22, a B cell specific marker; myelin associated glycoprotein (MAG), which is expressed on oligodendrocytes and Schwann cells; CD33, a myeloid differentiation antigen; and sialoadhesin, which is expressed only by a subpopulation of tissue macrophages. Involved in cell-cell interactions, sialoadhesin is structurally related to the 3 other listed members of the sialoadhesin family. CD169 is a sialic acid binding site of sialoadhesin. CD169 is a macrophage receptor expressed on stromal macrophages in many tissues, particularly found in lymph nodes, bone marrow and spleen.
Synonyms Sialoadhesin, Siglec-1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.