HLA Class II DQ Mouse Monoclonal Antibody [Clone ID: FN81]

CAT#: AM05947BT-N

HLA Class II DQ mouse monoclonal antibody, clone FN81, Biotin


USD 455.00

2 Weeks*

Size
    • 100 ug

Product Images

Specifications

Product Data
Clone Name FN81
Applications FC, IHC
Recommended Dilution Immunohistochemistry on Frozen Sections: ≤ 0.05 µg/ml (1/4000).
Recommended Positive Control: Human tonsil.
Has been described to work in Flow Cytometry.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Stimulated human B lymphocytes.
The antigen is HLA-DQ. The epitope has not been further characterized.
Specificity This Monoclonal antibody FN81 recognizes the Human HLA-DQ antigen.
Antigen Distribution on Isolated Cells: The HLA DQ antigen is present on approximately 10% of peripheral blood lymphocytes.
Formulation PBS, pH 7.2, with 0.05% Kathon as preservative and 5 mg/ml BSA as stabilizer.
Label: Biotin
State: Lyophilized purified IgG fraction.
Reconstitution Method Restore with 0.5 ml distilled water (= Stock solution).
Concentration 0.2 mg/ml
Purification Affinity Chromatography.
Conjugation Biotin
Storage Store lyophilized at 2-8°C.
Stock solution or aliquots of stock solution can be kept frozen at -20°C.
Do not freeze working dilutions.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Background HLA-DQ is an HLA class II antigen with homology to murine H-2A. HLA class II antigens are mainly expressed on specialized antigen presenting cells (APCs), dendritic cells, B-cells and macrophages. HLA class II antigen is presented on activated T-cells. HLA class II molecules present exogenously derived antigen to the T-cell receptor (TCR) on CD4+ T lymphocytes. Both chains in HLA-DQ are polymorphic. HLA-DQ is expressed after DR and DP during haemotopoietic progenitor cell development. It is strongly expressed in the thymic cortex.
Synonyms MHC Class II DQ
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.