CD34 Mouse Monoclonal Antibody [Clone ID: 4H5E7]
Specifications
Product Data | |
Clone Name | 4H5E7 |
Applications | ELISA, IF, IHC, WB |
Recommended Dilution | ELISA: 1/10000. Western Blot: 1/500 - 1/2000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of CD34 expressed in E. Coli. |
Specificity | Recognizes CD34 |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CD34 is a transmembrane glycoprotein with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells, endothelial cells and some fibroblasts. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells. CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence. |
Synonyms | Hematopoietic progenitor cell marker |
Reference Data |
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