CD20 (MS4A1) Mouse Monoclonal Antibody [Clone ID: 3E9D3C1G3]
Specifications
Product Data | |
Clone Name | 3E9D3C1G3 |
Applications | ELISA, IF, IHC |
Recommended Dilution | ELISA: 1/10000. Immunofluorescence: 1/200 - 1/1000. Immunohistochemistry on Paraffin Sections: 1/200 - 1/1000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | KLH conjugated Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of Human CD20 |
Specificity | Recognizes MS4A1/CD20. |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Database Link | |
Background | CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1. |
Synonyms | MS4A1, Leu-16, Bp35, B-cell marker |
Reference Data |
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